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KMID : 1098420140220050378
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Korean Journal of Medicinal Crop Science
2014 Volume.22 No. 5 p.378 ~ p.383
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Enhancement of Skin Immune Activities of Curcuma longa L. Leaf Extract by Ultra High Pressure Process
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Kim Nam-Young
Lee Hyeon-Yong
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Abstract
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Curcuma longa L. leaf was extracted by water at for 12 hours after being treatment of Ultra High Pressure under 500 MPa for 5-15 minute. The high pressure extraction for 15 minute (HPE15) was measured the highest extraction yield of 25.48% (w/w), compared to those from conventional extraction methods. The HPE15 showed the lowest cytotoxicity as 11.97% in adding of concentration. Also, HPE15 was measured the highest inhibition of hyaluronidase as 44.48% in adding . In addition, The production of NO from macrophages was measured as in adding of HPE15, which was lower than the those from others processes. Finally, HPE15 significantly reduced up to of production from UV-irradiation. These results suggest that the Curcuma longa Linne leaf extract from high pressure process might enhance the skin immune activities possibly by high elution of active components than other processes.
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KEYWORD
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Curcuma longa L., High Pressure Process, Skin Immune Activity
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